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ea0073oc7.1 | Oral Communications 7: Diabetes, Obesity, Metabolism and Nutrition | ECE2021

Circulating concentrations of TMAO is associated with all-cause mortality in subjects with Non-alcoholic fatty liver disease. Results from a dutch prospective cohort

Flores-Guerrero Jose L. , van Dijk Peter R. , Connelly Margery A. , Garcia Erwin , Navis Gerjan , Bakker Stephan J.L. , Dullaart Robin P.F.

ObjectiveDue to the increasing prevalence of Non-Alcoholic Fatty Liver Disease (NAFLD), it has become a global health challenge by being the most common cause of chronic liver disease. Recently, the microbiota has been linked to NAFLD, via altered bile acid and lipid metabolism. Whether serum Trimethylamine-N-oxide (TMAO), a gut microbiota-dependent metabolite, is associated with NAFLD and NAFLD health outcomes remains unclear. The aim was to investigate...

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Circulating concentrations of TMAO is associated with all-cause mortality in subjects with Non-alcoholic fatty liver disease. Results from a dutch prospective cohort

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